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Automatic Pharmaceutical Powder Filling Machine
Product Overview
Product Overview
SINOPED SGSFJ pharmaceutical powder filling machine is an automatic vial filling solution designed for accurate powder dosing, vacuum stoppering and capping applications in pharmaceutical manufacturing.
Developed for sterile powder injection production, this automatic powder filling machine integrates bottle feeding, precision screw filling, stopper insertion and aluminum cap sealing into a complete production system. It is widely used by pharmaceutical companies, biotechnology manufacturers and CDMO facilities that require reliable filling accuracy, stable production performance and GMP-compatible equipment.
The SGSFJ powder filling line can be connected with the SGLP bottle unscrambler to form a complete vial powder filling production line, helping manufacturers improve production efficiency while reducing manual operation requirements.
How the Powder Filling Machine Works
The SGSFJ vial powder filling machine uses a precision screw dosing mechanism to control powder volume during the filling process.
After empty vials enter the machine through the bottle feeding system, the powder is accurately measured and filled through single or double screw filling technology. The filling system is designed to handle different powder characteristics while maintaining consistent dosage accuracy.
After filling, the machine automatically performs vacuum stopper insertion to ensure proper sealing between the vial and stopper. The final capping process completes the container closure operation, producing sealed pharmaceutical powder products ready for further inspection or packaging.
Through an integrated automation design, the system combines powder filling, stoppering and capping operations in one continuous production process.
Technical Specifications
| Parameter | Specification |
| Product Model | SGSFJ |
| Equipment Type | Automatic Pharmaceutical Powder Filling Machine |
| Applicable Filling Range | 0.03-2g / 1-10g |
| Filling Method | Single Screw Filling / Double Screw Filling |
| Production Speed | Single Head: 30-50 bottles/min |
| Production Speed | Double Head: 50-80 bottles/min |
| Filling Accuracy | ±3% |
| Stoppering & Capping Pass Rate | ≥99% |
| Power Supply | 220V, 3.5KW |
| Compressed Air Pressure | 0.6-0.8MPa |
| Air Consumption | 10-30m³/h |
| Machine Weight | 1500kg |
| Machine Dimension Option 1 | 4000×2000×1750mm |
| Machine Dimension Option 2 | 5000×2000×1750mm |
Powder Filling Machine Selection Guide
Selecting the right pharmaceutical powder filling machine depends mainly on production capacity, filling volume and product characteristics.
For small-volume pharmaceutical powders ranging from 0.03g to 2g, the precision filling configuration is suitable for products requiring high dosing consistency. For larger powder volumes between 1g and 10g, the machine can be configured for higher filling capacity while maintaining stable accuracy.
Production speed is another important consideration. The single-head configuration provides a flexible solution for pilot production and medium-scale manufacturing, while the double-head configuration is recommended for commercial pharmaceutical production lines requiring higher output.
For manufacturers producing sterile powder injections, antibiotics, vaccines or biological products, the SGSFJ system provides an integrated solution combining filling, stoppering and capping functions.
Powder Filling Machine Comparison
Automatic Powder Filling Machine vs Manual Powder Filling
| Comparison Item | Automatic Powder Filling Machine | Manual Filling |
| Filling Accuracy | Controlled screw dosing, ±3% | Depends on operator skill |
| Production Efficiency | Continuous automated production | Low production capacity |
| Labor Requirement | Reduced labor input | High labor dependency |
| Product Consistency | Stable batch-to-batch performance | Higher variation |
| Production Environment | Suitable for pharmaceutical production | Limited application |
The automatic powder filling system provides better production repeatability and contamination control compared with manual filling methods, making it more suitable for modern pharmaceutical manufacturing facilities.
Single Head vs Double Head Filling Configuration
| Feature | Single Head System | Double Head System |
| Production Speed | 30-50 bottles/min | 50-80 bottles/min |
| Application | Flexible and medium production | High-volume manufacturing |
| Investment Level | Lower | Higher |
| Recommended Users | Pilot plants, small-medium factories | Commercial pharmaceutical manufacturers |
Applications of Pharmaceutical Powder Filling Machine
The SGSFJ automatic powder filling machine is mainly designed for pharmaceutical powder products that require precise dosing and reliable container closure.
Typical applications include sterile powder injection filling, antibiotic powder production, vaccine and biological product manufacturing, as well as other pharmaceutical formulations supplied in vial containers.
The machine is also suitable for CDMO manufacturers that need flexible production equipment capable of supporting multiple pharmaceutical products and batch sizes.
Installation and Maintenance
The SGSFJ powder filling machine should be installed in a suitable pharmaceutical production environment with stable electricity supply and compressed air availability.
Before operation, manufacturers should ensure that the production area meets required cleanliness conditions and that all product-contact components are properly cleaned and assembled.
Routine maintenance mainly focuses on the powder dosing system, screw filling components, stopper handling mechanism, capping system and pneumatic components. Regular inspection helps maintain filling accuracy and extends equipment service life.
Recommended maintenance includes checking filling screw wear, cleaning powder residue, verifying sensor performance and calibrating filling parameters according to production requirements.
Compliance and Industry Standards
The SGSFJ pharmaceutical powder filling machine is designed for applications requiring compliance with international pharmaceutical manufacturing practices.
The equipment can be integrated into GMP pharmaceutical production facilities and customized according to customer requirements for international markets.
Typical applicable standards include:
| Standard | Application |
| GMP (Good Manufacturing Practice) | Pharmaceutical production environment requirements |
| ISO Quality Management System | Equipment manufacturing quality control |
| CE Requirements | European market equipment compliance |
| Pharmaceutical Industry Guidelines | Sterile filling and contamination control requirements |
Troubleshooting Guide
| Problem | Possible Cause | Recommended Solution |
| Filling weight variation | Powder flow instability or incorrect screw adjustment | Check powder feeding condition and recalibrate filling parameters |
| Low filling accuracy | Filling screw wear or improper settings | Inspect screw system and adjust dosing parameters |
| Stopper insertion failure | Stopper feeding alignment issue | Check stopper supply and positioning system |
| Loose cap sealing | Incorrect capping adjustment | Adjust capping torque and cap positioning |
| Frequent machine shutdown | Sensor or electrical problem | Inspect sensors, wiring and control system |
Frequently Asked Questions
What is a pharmaceutical powder filling machine?
A pharmaceutical powder filling machine is an automated production system used to accurately fill powder products into vials or bottles and complete sealing operations such as stoppering and capping.
What products can be filled by the SGSFJ powder filling machine?
The machine is suitable for pharmaceutical powders including sterile injectable powders, antibiotics, vaccines, biological products and other vial-based powder formulations.
What is the filling accuracy of this powder filling equipment?
The standard filling accuracy is approximately ±3%, depending on powder properties, filling volume and production conditions.
Can this machine be integrated into a complete production line?
Yes. The SGSFJ powder filling machine can be combined with bottle unscrambling equipment and other pharmaceutical packaging machines to create a complete automatic vial powder filling line.
What is the production capacity of this machine?
The production capacity depends on the filling head configuration. The single-head model can reach 30-50 bottles per minute, while the double-head configuration can achieve 50-80 bottles per minute.
Why choose SINOPED powder filling machine?
SINOPED SGSFJ provides pharmaceutical manufacturers with a reliable automatic powder filling solution featuring precise screw dosing technology, integrated stoppering and capping functions, stable production performance and flexible configuration options.
Looking for detailed specifications, pricing, delivery information, or customized equipment solutions?
Contact our International Sales Manager Brucr for professional support regarding pharmaceutical machinery, production equipment, and customized manufacturing solutions.
Sales Manager: Brucr
WhatsApp: +86 13322335577
Our team provides global customers with equipment consultation, technical assistance, and project support.

